PTPRE a cytoplasmic and transmembrane receptor protein tyrosine phosphatase that regulates IL-10 and TNFA biosynthesis, myelination and cell-matrix adhesion, overexpression reduces tumor development Note: This description may include information from UniProtKB.
Protein type: EC; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine
Chromosomal Location of Human Ortholog: 10q26.2
Cellular Component:  cytoplasm; integral component of membrane; nucleus; plasma membrane
Molecular Function:  protein binding; transmembrane receptor protein tyrosine phosphatase activity
Biological Process:  negative regulation of insulin receptor signaling pathway; peptidyl-tyrosine dephosphorylation; protein dephosphorylation
Reference #:  P23469 (UniProtKB)
Alt. Names/Synonyms: DKFZp313F1310; FLJ57799; FLJ58245; HPTPE; protein tyrosine phosphatase epsilon; protein tyrosine phosphatase, receptor type, E; protein tyrosine phosphatase, receptor type, epsilon polypeptide; Protein-tyrosine phosphatase epsilon; PTPE; PTPRE; R-PTP-epsilon; Receptor-type tyrosine-protein phosphatase epsilon
Gene Symbols: PTPRE
Molecular weight: 80,642 Da
Basal Isoelectric point: 6.57  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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