PTPRE a cytoplasmic and transmembrane receptor protein tyrosine phosphatase that regulates IL-10 and TNFA biosynthesis, myelination and cell-matrix adhesion, overexpression reduces tumor development Note: This description may include information from UniProtKB.
Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine
Chromosomal Location of Human Ortholog: 10q26.2
Cellular Component:  cytoplasm; integral component of membrane; nucleus; plasma membrane
Molecular Function:  protein binding; transmembrane receptor protein tyrosine phosphatase activity
Biological Process:  negative regulation of insulin receptor signaling pathway; peptidyl-tyrosine dephosphorylation; protein dephosphorylation
Reference #:  P23469 (UniProtKB)
Alt. Names/Synonyms: DKFZp313F1310; FLJ57799; FLJ58245; HPTPE; protein tyrosine phosphatase epsilon; protein tyrosine phosphatase, receptor type, E; protein tyrosine phosphatase, receptor type, epsilon polypeptide; Protein-tyrosine phosphatase epsilon; PTPE; PTPRE; R-PTP-epsilon; Receptor-type tyrosine-protein phosphatase epsilon
Gene Symbols: PTPRE
Molecular weight: 80,642 Da
Basal Isoelectric point: 6.57  Predict pI for various phosphorylation states
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PTPRE

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein