TAUT Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily. Expressed abundantly in placenta and skeletal muscle, at intermediate levels in heart, brain, lung, kidney and pancreas and at low levels in liver. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 6 D1|6 40.73 cM
Cellular Component:  GABA-ergic synapse; integral component of membrane; integral component of plasma membrane; integral component of postsynaptic membrane; membrane; plasma membrane
Molecular Function:  beta-alanine transmembrane transporter activity; neurotransmitter:sodium symporter activity; symporter activity; taurine binding; taurine transmembrane transporter activity; taurine:sodium symporter activity
Biological Process:  beta-alanine transport; modulation of chemical synaptic transmission; neurotransmitter transport; taurine transport
Reference #:  O35316 (UniProtKB)
Alt. Names/Synonyms: AA589629; C80501; SC6A6; Slc6a6; Sodium- and chloride-dependent taurine transporter; solute carrier family 6 (neurotransmitter transporter, taurine), member 6; Solute carrier family 6 member 6; taurine/beta-alanine transporter; Taut
Gene Symbols: Slc6a6
Molecular weight: 69,856 Da
Basal Isoelectric point: 6.98  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene