calponin 1 Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. Belongs to the calponin family. Smooth muscle, and tissues containing significant amounts of smooth muscle. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Actin-binding; Contractile; Motility/polarity/chemotaxis; Myosin-binding
Chromosomal Location of Human Ortholog: 9|9 A3
Cellular Component:  cytoskeleton
Molecular Function:  actin binding; calmodulin binding
Biological Process:  actomyosin structure organization; negative regulation of vascular smooth muscle cell proliferation
Reference #:  Q08091 (UniProtKB)
Alt. Names/Synonyms: Basic calponin; calponin 1; Calponin H1, smooth muscle; Calponin-1; CN; Cnn1; CnnI
Gene Symbols: Cnn1
Molecular weight: 33,356 Da
Basal Isoelectric point: 9.05  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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calponin 1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene