TP2 In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins. Belongs to the nuclear transition protein 2 family. Note: This description may include information from UniProtKB.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 16p13.13
Cellular Component:  nuclear nucleosome
Molecular Function:  DNA binding
Biological Process:  multicellular organism development; positive regulation of protein processing; spermatogenesis, exchange of chromosomal proteins
Reference #:  Q05952 (UniProtKB)
Alt. Names/Synonyms: MGC116783; MGC116785; Nuclear transition protein 2; STP2; TNP2; TP-2; TP2; transition protein 2 (during histone to protamine replacement)
Gene Symbols: TNP2
Molecular weight: 15,641 Da
Basal Isoelectric point: 11.59  Predict pI for various phosphorylation states
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TP2

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB