TP2 In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins. Belongs to the nuclear transition protein 2 family. Note: This description may include information from UniProtKB.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 16p13.13
Cellular Component:  nuclear nucleosome
Molecular Function:  DNA binding
Biological Process:  multicellular organism development; positive regulation of protein processing; spermatogenesis, exchange of chromosomal proteins
Reference #:  Q05952 (UniProtKB)
Alt. Names/Synonyms: MGC116783; MGC116785; Nuclear transition protein 2; STP2; TNP2; TP-2; TP2; transition protein 2 (during histone to protamine replacement)
Gene Symbols: TNP2
Molecular weight: 15,641 Da
Basal Isoelectric point: 11.59  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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