TNKS1BP1 Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Actin-binding; Cell cycle regulation
Chromosomal Location of Human Ortholog: 11q12.1
Cellular Component:  CCR4-NOT complex; cell-cell adherens junction; cytoplasm; cytoskeleton; cytosol; nuclear heterochromatin; nucleus
Molecular Function:  ankyrin repeat binding; enzyme binding; protein binding; protein-containing complex binding
Biological Process:  cellular response to ionizing radiation; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; double-strand break repair; nuclear-transcribed mRNA poly(A) tail shortening; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-threonine phosphorylation; positive regulation of protein autophosphorylation; telomere maintenance via telomerase
Reference #:  Q9C0C2 (UniProtKB)
Alt. Names/Synonyms: 182 kDa tankyrase-1-binding protein; FLJ45975; KIAA1741; TAB182; tankyrase 1 binding protein 1; tankyrase 1 binding protein 1, 182kDa; tankyrase 1-binding protein of 182 kDa; TB182; testis secretory sperm-binding protein Li 206a; TNKS1BP1
Gene Symbols: TNKS1BP1
Molecular weight: 181,796 Da
Basal Isoelectric point: 4.77  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene