|
TNKS1BP1
Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
|
| Protein type: Actin-binding; Cell cycle regulation |
| Chromosomal Location of Human Ortholog: 11q12.1 |
|
Cellular Component:
CCR4-NOT complex; cell-cell adherens junction; cytoplasm; cytoskeleton; cytosol; nuclear heterochromatin; nucleus
|
|
Molecular Function:
ankyrin repeat binding; enzyme binding; protein binding; protein-containing complex binding
|
|
Biological Process:
cellular response to ionizing radiation; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; double-strand break repair; nuclear-transcribed mRNA poly(A) tail shortening; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-threonine phosphorylation; positive regulation of protein autophosphorylation; telomere maintenance via telomerase
|
|
Reference #:
Q9C0C2
(UniProtKB)
|
|
Alt. Names/Synonyms: 182 kDa tankyrase-1-binding protein; FLJ45975; KIAA1741; TAB182; tankyrase 1 binding protein 1; tankyrase 1 binding protein 1, 182kDa; tankyrase 1-binding protein of 182 kDa; TB182; testis secretory sperm-binding protein Li 206a; TNKS1BP1
|
|
Gene Symbols: TNKS1BP1
|
|
Molecular weight:
181,796 Da
|
|
Basal Isoelectric point:
4.77
Predict pI for various phosphorylation states
|
