AKAP2 Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 9q31.3
Cellular Component:  plasma membrane
Biological Process:  regulation of cell shape
Reference #:  Q9Y2D5 (UniProtKB)
Alt. Names/Synonyms: A kinase (PRKA) anchor protein 2; A-kinase anchor protein 2; A-kinase anchoring protein 2; AKAP-2; AKAP-KL; AKAP2; AKAPKL; DKFZp686H1948; KIAA0920; MISP2; PALM2; PALM2 and AKAP2 fusion; PALM2-AKAP2; PALM2-AKAP2 fusion; PALM2-AKAP2 protein; PALM2-AKAP2 readthrough; PALM2AKAP2; paralemmin 2; paralemmin-2; PRKA2; protein kinase A anchoring protein 2; Protein kinase A-anchoring protein 2; protein kinase A2
Gene Symbols: AKAP2
Molecular weight: 94,661 Da
Basal Isoelectric point: 5.04  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene