SFRS4 Plays a role in alternative splice site selection during pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10. Belongs to the splicing factor SR family. Note: This description may include information from UniProtKB.
Protein type: RNA splicing; RNA-binding; Spliceosome
Chromosomal Location of Human Ortholog: 4|4 D2.3
Cellular Component:  nuclear speck; nucleus
Molecular Function:  nucleic acid binding; RNA binding; sequence-specific mRNA binding
Biological Process:  hematopoietic progenitor cell differentiation; mRNA cis splicing, via spliceosome; mRNA processing; negative regulation of mRNA splicing, via spliceosome; regulation of alternative mRNA splicing, via spliceosome; RNA splicing
Reference #:  Q8VE97 (UniProtKB)
Alt. Names/Synonyms: 5730499P16Rik; AW550192; MNCb-261; MNCb-2616; serine and arginine-rich splicing factor 4; Serine/arginine-rich splicing factor 4; Sfrs4; Splicing factor, arginine/serine-rich 4; splicing factor, arginine/serine-rich 4 (SRp75); SRp75; Srsf4
Gene Symbols: Srsf4
Molecular weight: 55,979 Da
Basal Isoelectric point: 11.39  Predict pI for various phosphorylation states
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SFRS4

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene