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tensin 1
Involved in fibrillar adhesion formation. May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton. Ubiquitous. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis |
| Chromosomal Location of mouse Ortholog: 1 C3|1 38.17 cM |
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Cellular Component:
anchoring junction; cell-substrate junction; cytoplasm; cytoskeleton; focal adhesion
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Molecular Function:
actin binding; hydrolase activity; metal ion binding; phosphoprotein phosphatase activity
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Biological Process:
cell-substrate junction assembly; fibroblast migration
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Reference #:
E9Q0S6
(UniProtKB)
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Alt. Names/Synonyms: 1110018I21Rik; 1200014E20Rik; AI648117; E030018G17Rik; E030037J05Rik; Tensin 1; Tensin-1; Tns; Tns1
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Gene Symbols: Tns1
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Molecular weight:
201,383 Da
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Basal Isoelectric point:
7.76
Predict pI for various phosphorylation states
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