ARHGEF10L Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC. Detected in heart, liver, skeletal muscle, kidney and pancreas. 5 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Deacetylase; GEF; GEF, Rac/Rho; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 4|4 D3
Cellular Component:  cytoplasm; cytosol
Molecular Function:  GTPase activator activity; guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity
Biological Process:  actin cytoskeleton organization; positive regulation of stress fiber assembly; regulation of Rho protein signal transduction; SREBP signaling pathway
Reference #:  A2AWP8 (UniProtKB)
Alt. Names/Synonyms: 2810441C07Rik; ARGAL; Arhgef10l; GrinchGEF; Kiaa1626; mKIAA1626; Rho guanine nucleotide exchange factor (GEF) 10-like; Rho guanine nucleotide exchange factor 10-like protein
Gene Symbols: Arhgef10l
Molecular weight: 139,987 Da
Basal Isoelectric point: 5.56  Predict pI for various phosphorylation states
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ARHGEF10L

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene