SIPA1L3 Plays a critical role in epithelial cell morphogenesis, polarity, adhesion and cytoskeletal organization in the lens. Note: This description may include information from UniProtKB.
Protein type: GAP; GAP, Ras
Chromosomal Location of mouse Ortholog: 7|7 B1
Cellular Component:  apical part of cell; membrane; plasma membrane; stress fiber; tricellular tight junction
Molecular Function:  GTPase activator activity
Biological Process:  cytoskeleton organization; epithelial cell morphogenesis; establishment of epithelial cell polarity; eye development; hematopoietic progenitor cell differentiation; regulation of small GTPase mediated signal transduction
Reference #:  G3X9J0 (UniProtKB)
Alt. Names/Synonyms: 2610511M17Rik; SI1L3; signal-induced proliferation-associated 1 like 3; Signal-induced proliferation-associated 1-like protein 3; SIPA1-like protein 3; Sipa1l3; Sipa1l3 protein; SPA-1-like protein 3; Spal3
Gene Symbols: Sipa1l3
Molecular weight: 195,063 Da
Basal Isoelectric point: 8.58  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein