SEC31A Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. Belongs to the WD repeat SEC31 family. Abundantly and ubiquitously expressed. 10 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Oncoprotein; Vesicle
Chromosomal Location of Human Ortholog: 5|5 E4
Cellular Component:  COPII vesicle coat; COPII-coated ER to Golgi transport vesicle; cytoplasm; cytoplasmic vesicle; cytosol; endoplasmic reticulum; endoplasmic reticulum exit site; endosome; intracellular membrane-bounded organelle; perinuclear region of cytoplasm; vesicle coat
Molecular Function:  calcium-dependent protein binding; structural molecule activity
Biological Process:  cargo loading into COPII-coated vesicle; COPII-coated vesicle budding; endoplasmic reticulum organization; ER to Golgi vesicle-mediated transport; intracellular protein transport; protein transport; response to calcium ion; vesicle-mediated transport
Reference #:  Q3UPL0 (UniProtKB)
Alt. Names/Synonyms: 1810024J13Rik; ABP125; ABP130; AU042160; HSPC275; Protein transport protein Sec31A; SC31A; Sec31; Sec31 homolog A (S. cerevisiae); SEC31-like 1; SEC31-like protein 1; SEC31-related protein A; Sec31a; Sec31l1
Gene Symbols: Sec31a
Molecular weight: 133,569 Da
Basal Isoelectric point: 6.3  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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SEC31A

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene