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SREC-II
Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to SCARF1, it poorly mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Predominantly expressed in endothelial cells. Expressed in heart, placenta, lung, kidney, spleen, small intestine and ovary. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Cell adhesion; Membrane protein, integral |
| Chromosomal Location of mouse Ortholog: 16|16 A3 |
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Cellular Component:
membrane
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Molecular Function:
scavenger receptor activity
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Biological Process:
cell adhesion; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
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Reference #:
P59222
(UniProtKB)
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Alt. Names/Synonyms: AI194363; NSR1; Scarf1; Scarf2; Scatf1; Scavenger receptor class F member 2; scavenger receptor class F, member 1; scavenger receptor class F, member 2; scavenger receptor expressed by endothelial cells 2 (acetyl LDL receptor like); Scavenger receptor expressed by endothelial cells 2 protein; scavenger receptor type F; Sre; SREC-II; Srec2; SrecII; SRECRP-1; W53987; W65560
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Gene Symbols: Scarf2
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Molecular weight:
87,871 Da
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Basal Isoelectric point:
8.67
Predict pI for various phosphorylation states
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