CAP1 Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity. Belongs to the CAP family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Actin-binding; Cytoskeletal
Chromosomal Location of Human Ortholog: 4|4 D2.2
Cellular Component:  cortical actin cytoskeleton; cytoplasm; membrane; plasma membrane
Molecular Function:  actin binding; adenylate cyclase binding; protein binding
Biological Process:  actin cytoskeleton organization; actin polymerization or depolymerization; ameboidal-type cell migration; cell morphogenesis; cytoskeleton organization; establishment or maintenance of cell polarity; receptor-mediated endocytosis
Reference #:  P40124 (UniProtKB)
Alt. Names/Synonyms: adenylyl cyclase-associated CAP protein homolog 1 iae; adenylyl cyclase-associated CAP protein, yeast homolog 1; Adenylyl cyclase-associated protein 1; Cap; CAP 1; CAP, adenylate cyclase-associated protein 1 (yeast); Cap1; OTTMUSP00000009255; OTTMUSP00000009256; OTTMUSP00000009257
Gene Symbols: Cap1
Molecular weight: 51,565 Da
Basal Isoelectric point: 7.16  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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CAP1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene