EPB41L2
Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase. Widely expressed. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Cytoskeletal |
Chromosomal Location of mouse Ortholog: 10 A4|10 12.26 cM |
Cellular Component:
actin cytoskeleton; cell cortex; cell junction; COP9 signalosome; cytoplasm; cytoskeleton; membrane; nucleoplasm; plasma membrane
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Molecular Function:
actin binding; cytoskeletal protein binding; PH domain binding; protein binding; spectrin binding; structural molecule activity
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Biological Process:
actin cytoskeleton organization; actomyosin structure organization; cell cycle; cell division; cortical actin cytoskeleton organization; positive regulation of protein localization to cell cortex; regulation of cell shape
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Reference #:
O70318
(UniProtKB)
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Alt. Names/Synonyms: 4.1G; AW555191; Band 4.1-like protein 2; D10Ertd398; D10Ertd398e; E41L2; Epb4.1; Epb4.1l2; Epb41l2; erythrocyte membrane protein band 4.1 like 2; erythrocyte membrane protein band 4.1-like 2 retinal; erythrocyte protein band 4.1 like 2; erythrocyte protein band 4.1-like 2; erythrocyte protein band 4.1l2 long; erythrocyte protein band 4.1l2 middle; Generally expressed protein 4.1; NBL2
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Gene Symbols: Epb41l2
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Molecular weight:
109,940 Da
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Basal Isoelectric point:
5.31
Predict pI for various phosphorylation states
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