EPB41L2 Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase. Widely expressed. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 10 A4|10 12.26 cM
Cellular Component:  actin cytoskeleton; cell cortex region; cell junction; cytoplasm; cytoskeleton; membrane; nucleoplasm; nucleus; plasma membrane
Molecular Function:  actin binding; cytoskeletal protein binding; PH domain binding; protein binding; spectrin binding; structural molecule activity
Biological Process:  actin cytoskeleton organization; actomyosin structure organization; cell cycle; cell division; cortical actin cytoskeleton organization; positive regulation of protein localization to cell cortex; regulation of cell shape
Reference #:  O70318 (UniProtKB)
Alt. Names/Synonyms: 4.1G; AW555191; Band 4.1-like protein 2; D10Ertd398; D10Ertd398e; E41L2; Epb4.1; Epb4.1l2; Epb41l2; erythrocyte membrane protein band 4.1 like 2; erythrocyte membrane protein band 4.1-like 2 retinal; erythrocyte protein band 4.1 like 2; erythrocyte protein band 4.1-like 2; erythrocyte protein band 4.1l2 long; erythrocyte protein band 4.1l2 middle; Generally expressed protein 4.1; NBL2
Gene Symbols: Epb41l2
Molecular weight: 109,940 Da
Basal Isoelectric point: 5.31  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene