AKAP2 Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP. 5 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 4|4 B3
Cellular Component:  protein-containing complex
Molecular Function:  protein binding; protein domain specific binding; protein kinase A binding
Biological Process:  actin filament organization; protein heterooligomerization; protein localization; transmembrane receptor protein serine/threonine kinase signaling pathway
Reference #:  O54931 (UniProtKB)
Alt. Names/Synonyms: A kinase (PRKA) anchor protein 2; A kinase anchor protein 2; A-kinase anchor protein 2; AA959716; AI649048; AKAP expressed in kidney and lung; AKAP-2; AKAP-KL; Akap2; B230340M18Rik; OTTMUSP00000007734; OTTMUSP00000007735; OTTMUSP00000007736; OTTMUSP00000007737; PRKA2; Protein kinase A-anchoring protein 2
Gene Symbols: Akap2
Molecular weight: 98,579 Da
Basal Isoelectric point: 5.13  Predict pI for various phosphorylation states
Select Structure to View Below

AKAP2

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene