REXO2
3'-to-5' exoribonuclease specific for small oligoribonucleotides. Active on small (primarily </=5 nucleotides in length) single-stranded RNA and DNA oligomers. May have a role in cellular nucleotide recycling. Belongs to the oligoribonuclease family. 3 alternative initiation human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: EC 3.1.-.-; Hydrolase; Mitochondrial; Ribonuclease |
Chromosomal Location of mouse Ortholog: 9|9 A5.3 |
Cellular Component:
cytoplasm; focal adhesion; mitochondrial intermembrane space; mitochondrial matrix; mitochondrion; nucleolus; nucleus
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Molecular Function:
3'-5' exonuclease activity; 3'-5'-DNA exonuclease activity; 3'-5'-RNA exonuclease activity; exonuclease activity; hydrolase activity; magnesium ion binding; metal ion binding; nuclease activity; nucleic acid binding
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Biological Process:
nucleobase-containing compound metabolic process
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Reference #:
Q9D8S4
(UniProtKB)
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Alt. Names/Synonyms: 1810038D15Rik; AW107347; Oligoribonuclease, mitochondrial; ORN; Rex; Rex2; REX2, RNA exonuclease 2 homolog; REX2, RNA exonuclease 2 homolog (S. cerevisiae); Rexo2; RNA exonuclease 2; RNA exonuclease 2 homolog; Sfn; Small fragment nuclease; Smfn
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Gene Symbols: Rexo2
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Molecular weight:
26,739 Da
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Basal Isoelectric point:
6.67
Predict pI for various phosphorylation states
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