VDAC3 Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. Belongs to the eukaryotic mitochondrial porin family. Widely expressed. Highest in testis. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Channel, misc.; Membrane protein, integral; Mitochondrial
Chromosomal Location of mouse Ortholog: 8 A2|8 11.42 cM
Cellular Component:  integral component of membrane; membrane; mitochondrial outer membrane; mitochondrion; pore complex; rough endoplasmic reticulum; synaptic vesicle
Molecular Function:  nucleotide binding; porin activity; voltage-gated anion channel activity
Biological Process:  anion transmembrane transport; behavioral fear response; chemical synaptic transmission; ion transport; learning; neuron-neuron synaptic transmission; regulation of cilium assembly; transmembrane transport
Reference #:  Q60931 (UniProtKB)
Alt. Names/Synonyms: channel protein VDAC3; MGC102096; mitochondrial outer membrane protein; mVDAC3; Outer mitochondrial membrane protein porin 3; VDAC-3; Vdac3; voltage-dependent anion channel 3; Voltage-dependent anion-selective channel protein 3
Gene Symbols: Vdac3
Molecular weight: 30,753 Da
Basal Isoelectric point: 8.96  Predict pI for various phosphorylation states
CST Pathways:  Warburg Effect
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene