|
VDAC3
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. Belongs to the eukaryotic mitochondrial porin family. Widely expressed. Highest in testis. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
|
| Protein type: Channel, misc.; Membrane protein, integral; Mitochondrial |
| Chromosomal Location of mouse Ortholog: 8 A2|8 11.42 cM |
|
Cellular Component:
integral component of membrane; membrane; mitochondrial outer membrane; mitochondrion; pore complex; rough endoplasmic reticulum; synaptic vesicle
|
|
Molecular Function:
nucleotide binding; porin activity; voltage-gated anion channel activity
|
|
Biological Process:
anion transmembrane transport; behavioral fear response; chemical synaptic transmission; ion transport; learning; neuron-neuron synaptic transmission; regulation of cilium assembly; transmembrane transport
|
|
Reference #:
Q60931
(UniProtKB)
|
|
Alt. Names/Synonyms: channel protein VDAC3; MGC102096; mitochondrial outer membrane protein; mVDAC3; Outer mitochondrial membrane protein porin 3; VDAC-3; Vdac3; voltage-dependent anion channel 3; Voltage-dependent anion-selective channel protein 3
|
|
Gene Symbols: Vdac3
|
|
Molecular weight:
30,753 Da
|
|
Basal Isoelectric point:
8.96
Predict pI for various phosphorylation states
|
|
CST Pathways:
Warburg Effect
|
