UDPase Hydrolyzes preferentially nucleoside 5'-diphosphates, nucleoside 5'-triphosphates are hydrolyzed only to a minor extent. The order of activity with different substrates is UDP Belongs to the GDA1/CD39 NTPase family. Ubiquitous. Highest expression in testis and lowest in bladder. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC; Hydrolase; Membrane protein, integral; Membrane protein, multi-pass; Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine
Chromosomal Location of Human Ortholog: 14|14 D2
Cellular Component:  integral component of autophagosome membrane; integral component of Golgi membrane
Molecular Function:  uridine-diphosphatase activity
Reference #:  Q9DBT4 (UniProtKB)
Alt. Names/Synonyms: 1200014F22Rik; 4930513O14Rik; A430102M06Rik; AI414893; Ectonucleoside triphosphate diphosphohydrolase 4; ENTP4; Entpd4; Lalp70; Lysal1; lysosomal apyrase-like 1; Lysosomal apyrase-like protein of 70 kDa; mKIAA0392; NTPDase 4; UDPase; Uridine-diphosphatase
Gene Symbols: Entpd4
Molecular weight: 69,746 Da
Basal Isoelectric point: 8.31  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene