SCS-beta a mitochondrial enzyme that catalyzes the phosphorylation of NTP, where N = adenosine or guanosine, in the tricarboxylic acid cycle. Catalyzes the following: ATP + succinate + CoA = ADP + succinyl-CoA + phosphate. Two splice variant isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - citrate (TCA) cycle; Carbohydrate Metabolism - propanoate; EC 6.2.1.5; Ligase; Mitochondrial
Chromosomal Location of Human Ortholog: 14|14 D3
Cellular Component:  mitochondrion; myelin sheath
Molecular Function:  ATP binding; catalytic activity; ligase activity; metal ion binding; nucleotide binding; succinate-CoA ligase (ADP-forming) activity; succinate-CoA ligase activity
Biological Process:  metabolic process; succinate metabolic process; succinyl-CoA metabolic process; tricarboxylic acid cycle
Reference #:  Q9Z2I9 (UniProtKB)
Alt. Names/Synonyms: 4930547K18Rik; ATP-specific succinyl-CoA synthetase subunit beta; SCS-betaA; SUCB1; Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; succinate-Coenzyme A ligase, ADP-forming, beta subunit; Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase beta-A chain; Sucla2
Gene Symbols: Sucla2
Molecular weight: 50,114 Da
Basal Isoelectric point: 6.57  Predict pI for various phosphorylation states
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SCS-beta

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene