YPEL5 Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Required for normal cell proliferation. Belongs to the yippee family. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 2p23.1
Cellular Component:  extracellular region; ficolin-1-rich granule lumen; midbody; mitotic spindle pole; nucleus; tertiary granule lumen; ubiquitin ligase complex
Molecular Function:  metal ion binding; protein binding
Biological Process:  cell proliferation; neutrophil degranulation
Reference #:  P62699 (UniProtKB)
Alt. Names/Synonyms: CGI-127; Protein yippee-like 5; yippee like 5; yippee protein; yippee-like 5 (Drosophila); YPEL5
Gene Symbols: YPEL5
Molecular weight: 13,842 Da
Basal Isoelectric point: 6.82  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene