GCP2 Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. Belongs to the TUBGCP family. Ubiquitously expressed. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 7|7 F4
Cellular Component:  centrosome; cytoplasm; cytoskeleton; equatorial microtubule organizing center; gamma-tubulin complex; gamma-tubulin small complex; microtubule; microtubule organizing center; nucleoplasm; spindle pole
Molecular Function:  gamma-tubulin binding
Biological Process:  cytoplasmic microtubule organization; meiotic cell cycle; microtubule cytoskeleton organization; microtubule nucleation; microtubule nucleation by interphase microtubule organizing center; mitotic cell cycle; spindle assembly
Reference #:  Q921G8 (UniProtKB)
Alt. Names/Synonyms: 1700022B05Rik; Gamma-tubulin complex component 2; GCP-2; Gcp2; Tubgcp2; tubulin, gamma complex associated protein 2
Gene Symbols: Tubgcp2
Molecular weight: 103,223 Da
Basal Isoelectric point: 6.31  Predict pI for various phosphorylation states
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GCP2

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene