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SMS
Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM). Belongs to the spermidine/spermine synthase family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Amino Acid Metabolism - arginine and proline; Amino Acid Metabolism - cysteine and methionine; EC 2.5.1.22; Other Amino Acids Metabolism - beta-alanine; Other Amino Acids Metabolism - glutathione; Transferase |
| Chromosomal Location of mouse Ortholog: X F4|X 72.48 cM |
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Cellular Component:
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Molecular Function:
spermine synthase activity; transferase activity
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Biological Process:
polyamine biosynthetic process; spermine biosynthetic process; spermine metabolic process
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Reference #:
P97355
(UniProtKB)
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Alt. Names/Synonyms: AI427066; Gy; gyro; Sms; Spermidine aminopropyltransferase; Spermine synthase; SpmST; SPMSY; SPSY
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Gene Symbols: Sms
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Molecular weight:
41,313 Da
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Basal Isoelectric point:
4.9
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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