DUSP19 Has a dual specificity toward Ser/Thr and Tyr-containing proteins. Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. Expressed in the heart, lung, liver, and pancreas. The expression level in the pancreas is the highest. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC 3.1.3.16; EC 3.1.3.48; Motility/polarity/chemotaxis; Protein phosphatase, dual-specificity
Chromosomal Location of Human Ortholog: 2q32.1
Cellular Component: 
Molecular Function:  MAP-kinase scaffold activity; mitogen-activated protein kinase kinase kinase binding; protein binding; protein kinase activator activity; protein kinase inhibitor activity; protein tyrosine phosphatase activity
Biological Process:  activation of protein kinase activity; negative regulation of JNK cascade; negative regulation of JUN kinase activity; negative regulation of protein kinase activity; peptidyl-tyrosine dephosphorylation; positive regulation of JNK cascade; positive regulation of JUN kinase activity; positive regulation of MAPK cascade; positive regulation of protein kinase activity
Reference #:  Q8WTR2 (UniProtKB)
Alt. Names/Synonyms: dual specificity phosphatase 19; Dual specificity phosphatase TS-DSP1; Dual specificity protein phosphatase 19; DUS19; DUSP17; DUSP19; LMW-DSP3; LMWDSP3; Low molecular weight dual specificity phosphatase 3; MGC138210; Protein phosphatase SKRP1; SAPK pathway-regulating phosphatase 1; SKRP1; Stress-activated protein kinase pathway-regulating phosphatase 1; TS-DSP1
Gene Symbols: DUSP19
Molecular weight: 24,194 Da
Basal Isoelectric point: 6.11  Predict pI for various phosphorylation states
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DUSP19

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein