calponin 1 Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. Belongs to the calponin family. Smooth muscle, and tissues containing significant amounts of smooth muscle. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Actin-binding; Contractile; Motility/polarity/chemotaxis; Myosin-binding
Cellular Component:  cytoskeleton
Molecular Function:  actin binding; calmodulin binding; protein binding
Biological Process:  actomyosin structure organization; negative regulation of vascular smooth muscle cell proliferation
Reference #:  P26932 (UniProtKB)
Alt. Names/Synonyms: calponin 1; calponin 1, basic, smooth muscle; Calponin-1; CLPO; CNN1
Gene Symbols: CNN1
Molecular weight: 32,361 Da
Basal Isoelectric point: 9.3  Predict pI for various phosphorylation states
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calponin 1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene