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ALDOA
Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein. Belongs to the class I fructose-bisphosphate aldolase family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Carbohydrate Metabolism - fructose and mannose; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - pentose phosphate pathway; EC 4.1.2.13; Lyase; Mitochondrial |
| Chromosomal Location of mouse Ortholog: 7|7 F3 |
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Cellular Component:
actin cytoskeleton; cytoplasm; cytosol; extracellular exosome; heterochromatin; membrane; plasma membrane; protein-containing complex; sperm fibrous sheath; sperm head; Z disc
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Molecular Function:
cytoskeletal protein binding; fructose binding; fructose-bisphosphate aldolase activity; identical protein binding; protease binding
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Biological Process:
ATP biosynthetic process; binding of sperm to zona pellucida; canonical glycolysis; fructose 1,6-bisphosphate metabolic process; fructose metabolic process; glycolytic process; glycolytic process through fructose-6-phosphate; methylglyoxal biosynthetic process; muscle cell cellular homeostasis; positive regulation of cell migration; regulation of cell shape; striated muscle contraction
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Reference #:
P05064
(UniProtKB)
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Alt. Names/Synonyms: Ald; Aldo-1; Aldo1; Aldoa; Aldolase 1; aldolase 1, A isoform; aldolase A, fructose-bisphosphate; Fructose-bisphosphate aldolase A; MGC107164; Muscle-type aldolase; OTTMUSP00000030463; OTTMUSP00000030464
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Gene Symbols: Aldoa
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Molecular weight:
39,356 Da
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Basal Isoelectric point:
8.3
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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