|
VDAC3
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. Belongs to the eukaryotic mitochondrial porin family. Widely expressed. Highest in testis. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
|
| Protein type: Channel, misc.; Membrane protein, integral; Mitochondrial |
| Chromosomal Location of Human Ortholog: 8p11.21 |
|
Cellular Component:
mitochondrion; pore complex
|
|
Molecular Function:
nucleotide binding; porin activity; protein binding; voltage-gated anion channel activity
|
|
Biological Process:
adenine transport; anion transmembrane transport; behavioral fear response; inorganic anion transport; learning; neuron-neuron synaptic transmission; regulation of cilium assembly
|
|
Reference #:
Q9Y277
(UniProtKB)
|
|
Alt. Names/Synonyms: HD-VDAC3; hVDAC3; Outer mitochondrial membrane protein porin 3; VDAC-3; VDAC3; voltage dependent anion channel 3; voltage-dependent anion channel 3; Voltage-dependent anion-selective channel protein 3
|
|
Gene Symbols: VDAC3
|
|
Molecular weight:
30,659 Da
|
|
Basal Isoelectric point:
8.84
Predict pI for various phosphorylation states
|
|
CST Pathways:
Warburg Effect
|
