VDAC3 Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. Belongs to the eukaryotic mitochondrial porin family. Widely expressed. Highest in testis. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Channel, misc.; Membrane protein, integral; Mitochondrial
Chromosomal Location of Human Ortholog: 8p11.21
Cellular Component:  mitochondrion; pore complex
Molecular Function:  nucleotide binding; porin activity; protein binding; voltage-gated anion channel activity
Biological Process:  adenine transport; anion transmembrane transport; behavioral fear response; inorganic anion transport; learning; neuron-neuron synaptic transmission; regulation of cilium assembly
Reference #:  Q9Y277 (UniProtKB)
Alt. Names/Synonyms: HD-VDAC3; hVDAC3; Outer mitochondrial membrane protein porin 3; VDAC-3; VDAC3; voltage dependent anion channel 3; voltage-dependent anion channel 3; Voltage-dependent anion-selective channel protein 3
Gene Symbols: VDAC3
Molecular weight: 30,659 Da
Basal Isoelectric point: 8.84  Predict pI for various phosphorylation states
CST Pathways:  Warburg Effect
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein