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EML4
May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic. Belongs to the WD repeat EMAP family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Cytoskeletal |
| Chromosomal Location of human Ortholog: 2p21 |
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Cellular Component:
cytoplasm; cytosol; microtubule; microtubule cytoskeleton; microtubule organizing center; midbody; mitotic spindle
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Molecular Function:
alpha-tubulin binding; beta-tubulin binding; microtubule binding; protein binding; protein self-association
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Biological Process:
attachment of spindle microtubules to kinetochore; cell division; microtubule cytoskeleton organization; microtubule-based process; mitotic cell cycle; mitotic metaphase plate congression
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Reference #:
Q9HC35
(UniProtKB)
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Alt. Names/Synonyms: C2orf2; DKFZp686P18118; echinoderm microtubule associated protein like 4; Echinoderm microtubule-associated protein-like 4; ELP120; EMAL4; EMAP like 4; EMAP-4; EMAPL4; EML4; FLJ10942; FLJ32318; Restrictedly overexpressed proliferation-associated protein; Ropp 120; ROPP120
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Gene Symbols: EML4
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Molecular weight:
108,916 Da
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Basal Isoelectric point:
5.96
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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