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WDR54
a WD40 repeat protein. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. Two alternatively spliced human isoforms have been described. Note: This description may include information from UniProtKB.
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| Protein type: Unknown function |
| Chromosomal Location of human Ortholog: 2p13.1 |
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Cellular Component:
axoneme; vesicle
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Molecular Function:
protein homodimerization activity
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Biological Process:
cilium assembly; negative regulation of receptor internalization; regulation of epidermal growth factor receptor signaling pathway; regulation of MAPK cascade
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Reference #:
Q9H977
(UniProtKB)
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Alt. Names/Synonyms: FLJ12953; WD repeat domain 54; WD repeat-containing protein 54; WDR54
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Gene Symbols: WDR54
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Molecular weight:
35,891 Da
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Basal Isoelectric point:
5.77
Predict pI for various phosphorylation states
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