ELP3 a histone acetyltransferase. A subunit of the Elongator complex, which associates with the elongating, hyperphosphorylated form of RNA polymerase II. Note: This description may include information from UniProtKB.
Protein type: Acetyltransferase; EC 2.3.1.48
Chromosomal Location of Human Ortholog: 8p21.1
Cellular Component:  cytoplasm; Elongator holoenzyme complex; nucleolus; transcription elongation factor complex
Molecular Function:  acetyltransferase activity; histone acetyltransferase activity; iron-sulfur cluster binding; metal ion binding; phosphorylase kinase regulator activity; protein binding
Biological Process:  central nervous system development; histone acetylation; neuron migration; positive regulation of cell migration; regulation of protein kinase activity; regulation of transcription by RNA polymerase II; transcription elongation from RNA polymerase II promoter; tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation
Reference #:  Q9H9T3 (UniProtKB)
Alt. Names/Synonyms: elongation protein 3 homolog (S. cerevisiae); Elongator complex protein 3; ELP3; FLJ10422; hELP3; KAT9
Gene Symbols: ELP3
Molecular weight: 62,259 Da
Basal Isoelectric point: 9.04  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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ELP3

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB