TBC1D1 May act as a GTPase-activating protein for Rab family protein(s). May play a role in the cell cycle and differentiation of various tissues. Involved in the trafficking and translocation of GLUT4-containing vesicles and insulin-stimulated glucose uptake into cells. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: GAP; GAP, Rab; Ubiquitin-specific protease
Chromosomal Location of Human Ortholog: 4p14
Cellular Component:  cytosol; nucleus
Molecular Function:  protein binding
Biological Process:  membrane organization; regulation of protein localization
Reference #:  Q86TI0 (UniProtKB)
Alt. Names/Synonyms: KIAA1108; TBC; TBC1; TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1; TBC1 domain family member 1; TBC1D1; TBCD1
Gene Symbols: TBC1D1
Molecular weight: 133,084 Da
Basal Isoelectric point: 6.52  Predict pI for various phosphorylation states
CST Pathways:  Insulin Receptor Signaling
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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TBC1D1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB