NPM-ALK Chimeric protein, having the amino-terminal nucleoplasmin domain from NPM1 and the carboxy-terminal protein tyrosine kinase domain of ALK.
Protein type: Alk family; Kinase, protein; Protein kinase, TK; Protein kinase, tyrosine (receptor); TK group
Cellular Component: 
Disease: Neuroblastoma, Susceptibility To; Neuroblastoma, Susceptibility To, 3
Reference #:  AAA58698 (GenPept)
Alt. Names/Synonyms: ALK; ALK tyrosine kinase receptor; anaplastic lymphoma kinase; anaplastic lymphoma receptor tyrosine kinase; CD246; CD246 antigen; NBLST3; NPM-ALK; nucleophosmin-anaplastic lymphoma kinase fusion protein
Gene Symbols: NPM/ALK
Molecular weight: 75,314 Da
Basal Isoelectric point: 6.44  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  cBioPortal  |  Wikipedia  |  GenPept