EIF1 Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA. Belongs to the SUI1 family. Note: This description may include information from UniProtKB.
Protein type: Translation; Translation initiation
Chromosomal Location of human Ortholog: 17q21.2
Cellular Component:  cytoplasm; eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; multi-eIF complex; nucleus
Molecular Function:  protein binding; ribosomal small subunit binding; RNA binding; translation factor activity, RNA binding; translation initiation factor activity
Biological Process:  dosage compensation by inactivation of X chromosome; regulation of translational initiation; translational initiation
Reference #:  P41567 (UniProtKB)
Alt. Names/Synonyms: A121; EIF-1; EIF1; EIF1A; Eukaryotic translation initiation factor 1; ISO1; Protein translation factor SUI1 homolog; SUI1; Sui1iso1
Gene Symbols: EIF1
Molecular weight: 12,732 Da
Basal Isoelectric point: 6.9  Predict pI for various phosphorylation states
CST Pathways:  Translation: eIF2  |  Translational Control
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein