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EIF1
Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA. Belongs to the SUI1 family. Note: This description may include information from UniProtKB.
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| Protein type: Translation; Translation initiation |
| Chromosomal Location of human Ortholog: 17q21.2 |
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Cellular Component:
cytoplasm; eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; multi-eIF complex; nucleus
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Molecular Function:
protein binding; ribosomal small subunit binding; RNA binding; translation factor activity, RNA binding; translation initiation factor activity
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Biological Process:
dosage compensation by inactivation of X chromosome; regulation of translational initiation; translational initiation
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Reference #:
P41567
(UniProtKB)
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Alt. Names/Synonyms: A121; EIF-1; EIF1; EIF1A; Eukaryotic translation initiation factor 1; ISO1; Protein translation factor SUI1 homolog; SUI1; Sui1iso1
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Gene Symbols: EIF1
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Molecular weight:
12,732 Da
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Basal Isoelectric point:
6.9
Predict pI for various phosphorylation states
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CST Pathways:
Translation: eIF2
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Translational Control
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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