hnRNP H1 This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG). Note: This description may include information from UniProtKB.
Protein type: RNA splicing; RNA-binding; Spliceosome
Chromosomal Location of Human Ortholog: 5q35.3
Cellular Component:  catalytic step 2 spliceosome; cytosol; nucleoplasm; nucleus
Molecular Function:  poly(U) RNA binding; protein binding; RNA binding
Biological Process:  fibroblast growth factor receptor signaling pathway; mRNA splicing, via spliceosome; regulation of RNA splicing; RNA metabolic process; RNA processing
Reference #:  P31943 (UniProtKB)
Alt. Names/Synonyms: DKFZp686A15170; Heterogeneous nuclear ribonucleoprotein H; Heterogeneous nuclear ribonucleoprotein H, N-terminally processed; heterogeneous nuclear ribonucleoprotein H1 (H); HNRH1; hnRNP H; hnRNPH; HNRNPH1; HNRPH; HNRPH1
Gene Symbols: HNRNPH1
Molecular weight: 49,229 Da
Basal Isoelectric point: 5.89  Predict pI for various phosphorylation states
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hnRNP H1

Protein Structure Not Found.


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