TKT Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. Homodimer. Belongs to the transketolase family. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - pentose phosphate pathway; EC; Transferase
Chromosomal Location of Human Ortholog: 3p21.1
Cellular Component:  cytosol; nuclear body; nuclear speck; nucleoplasm; peroxisome
Molecular Function:  cofactor binding; metal ion binding; protein binding; protein homodimerization activity; transketolase activity
Biological Process:  glyceraldehyde-3-phosphate biosynthetic process; pentose-phosphate shunt; pentose-phosphate shunt, non-oxidative branch; regulation of growth; xylulose biosynthetic process
Disease: Short Stature, Developmental Delay, And Congenital Heart Defects
Reference #:  P29401 (UniProtKB)
Alt. Names/Synonyms: FLJ34765; TK; TKT; TKT1; Transketolase
Gene Symbols: TKT
Molecular weight: 67,878 Da
Basal Isoelectric point: 7.58  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein