DOCK10 iso3 Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP.
Protein type: GEF; GEF, Rac/Rho; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 2q36.2
Cellular Component:  cytoplasm; cytosol; dendritic spine; nucleoplasm; nucleus
Molecular Function:  guanyl-nucleotide exchange factor activity
Biological Process:  B cell homeostasis; dendritic spine morphogenesis; marginal zone B cell differentiation; positive regulation of GTPase activity; regulation of cell migration; small GTPase mediated signal transduction
Reference #:  Q96BY6-3 (UniProtKB)
Alt. Names/Synonyms: dedicator of cytokinesis 10; Dedicator of cytokinesis protein 10; DOC10; DOCK10; DOCK10 iso3; dopamine receptor interacting protein 2; DRIP2; KIAA0694; Nbla10300; ZIZ3; Zizimin-3; zizimin3
Gene Symbols: DOCK10
Molecular weight: 249,491 Da
Basal Isoelectric point: 6.76  Predict pI for various phosphorylation states
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DOCK10 iso3

Protein Structure Not Found.


Cross-references to other databases:  Pfam  |  ENZYME  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein