LDH-B an enzyme that participates in the final step of anaerobic glycolysis. Catalyzes the conversion of (S)-lactate + NAD+ into pyruvate + NADH. Note: This description may include information from UniProtKB.
Protein type: Amino Acid Metabolism - cysteine and methionine; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - propanoate; Carbohydrate Metabolism - pyruvate; EC; Oxidoreductase
Chromosomal Location of Human Ortholog: 12p12.1
Cellular Component:  cytoplasm; cytosol; membrane raft
Molecular Function:  identical protein binding; L-lactate dehydrogenase activity; protein binding
Biological Process:  carbohydrate metabolic process; oxidation-reduction process; pyruvate metabolic process
Disease: Lactate Dehydrogenase B Deficiency
Reference #:  P07195 (UniProtKB)
Alt. Names/Synonyms: L-lactate dehydrogenase B chain; lactate dehydrogenase B; LDH heart subunit; LDH-B; LDH-H; LDHB; Renal carcinoma antigen NY-REN-46; TRG-5
Gene Symbols: LDHB
Molecular weight: 36,638 Da
Basal Isoelectric point: 5.71  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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