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ACTA1
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Belongs to the actin family. Note: This description may include information from UniProtKB.
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| Protein type: Cell development/differentiation; Contractile; Cytoskeletal; Motility/polarity/chemotaxis |
| Chromosomal Location of human Ortholog: 1q42.13 |
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Cellular Component:
actin cytoskeleton; actin filament; cell body; cytosol; filopodium; lamellipodium; sarcomere; stress fiber; striated muscle thin filament
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Molecular Function:
ADP binding; ATP binding; myosin binding; protein binding; structural constituent of cytoskeleton
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Biological Process:
cellular response to organonitrogen compound; mesenchyme migration; muscle contraction; muscle filament sliding; positive regulation of gene expression; response to extracellular stimulus; response to lithium ion; response to mechanical stimulus; response to steroid hormone; skeletal muscle fiber adaptation; skeletal muscle fiber development; skeletal muscle thin filament assembly
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Disease: Myopathy, Congenital, With Fiber-type Disproportion; Myopathy, Scapulohumeroperoneal; Nemaline Myopathy 3
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Reference #:
P68133
(UniProtKB)
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Alt. Names/Synonyms: ACTA; ACTA1; actin alpha 1, skeletal muscle; actin, alpha 1, skeletal muscle; Actin, alpha skeletal muscle; Actin, alpha skeletal muscle, intermediate form; ACTS; alpha skeletal muscle actin; Alpha-actin-1; ASMA; CFTD; CFTD1; CFTDM; MPFD; NEM1; NEM2; NEM3; nemaline myopathy type 3; SHPM
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Gene Symbols: ACTA1
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Molecular weight:
42,051 Da
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Basal Isoelectric point:
5.23
Predict pI for various phosphorylation states
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CST Pathways:
Death Receptor Signaling
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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