PGK1 an apparent multifunctional protein. A glycolytic enzyme and a polymerase alpha cofactor protein (primer recognition protein). Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 2.7.2.3; Kinase, other
Chromosomal Location of Human Ortholog: Xq21.1
Cellular Component:  cytosol; extracellular space; membrane raft
Molecular Function:  ATP binding; phosphoglycerate kinase activity; protein binding; protein-disulfide reductase activity
Biological Process:  canonical glycolysis; cellular response to hypoxia; epithelial cell differentiation; gluconeogenesis; glycolytic process; negative regulation of angiogenesis; phosphorylation; plasminogen activation
Disease: Phosphoglycerate Kinase 1 Deficiency
Reference #:  P00558 (UniProtKB)
Alt. Names/Synonyms: Cell migration-inducing gene 10 protein; MGC117307; MGC142128; MGC8947; MIG10; PGK1; PGKA; Phosphoglycerate kinase 1; Primer recognition protein 2; PRP 2
Gene Symbols: PGK1
Molecular weight: 44,615 Da
Basal Isoelectric point: 8.3  Predict pI for various phosphorylation states
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PGK1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene