GSR a class-I pyridine nucleotide-disulfide oxidoreductase. Maintains high levels of reduced glutathione in the cytosol. Alternative initiation results in a mitochondrial and a cytoplasmic isoform. Note: This description may include information from UniProtKB.
Protein type: EC 1.8.1.7; Other Amino Acids Metabolism - glutathione; Oxidoreductase
Chromosomal Location of Human Ortholog: 8p12
Cellular Component:  cytosol; external side of plasma membrane; mitochondrial matrix
Molecular Function:  electron transfer activity; NADP binding
Biological Process:  cellular oxidant detoxification; cellular response to oxidative stress; electron transport chain; nucleobase-containing small molecule interconversion
Reference #:  P00390 (UniProtKB)
Alt. Names/Synonyms: GLUR; glutathione reductase; Glutathione reductase, mitochondrial; GR; GRase; GRD1; GSHR; GSR; MGC78522
Gene Symbols: GSR
Molecular weight: 56,257 Da
Basal Isoelectric point: 8.74  Predict pI for various phosphorylation states
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GSR

Protein Structure Not Found.


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