STX8
Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER. Belongs to the syntaxin family. Highly expressed in heart. Also found in brain, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas. Note: This description may include information from UniProtKB.
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Protein type: Membrane protein, integral |
Chromosomal Location of human Ortholog: 17p13.1 |
Cellular Component:
cytosol; early endosome; endomembrane system; endoplasmic reticulum; endosome; late endosome; perinuclear region of cytoplasm; phagocytic vesicle; plasma membrane; recycling endosome; SNARE complex; trans-Golgi network; vesicle
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Molecular Function:
chloride channel inhibitor activity; protein binding; SNAP receptor activity; SNARE binding; syntaxin binding; ubiquitin protein ligase binding
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Biological Process:
cellular response to type II interferon; early endosome to late endosome transport; intracellular protein transport; regulation of protein localization to plasma membrane; vesicle docking; vesicle fusion
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Reference #:
Q9UNK0
(UniProtKB)
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Alt. Names/Synonyms: CARB; CIP-1-associated regulator of cyclin B; STX8; syntaxin 8; Syntaxin-8
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Gene Symbols: STX8
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Molecular weight:
26,907 Da
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Basal Isoelectric point:
4.91
Predict pI for various phosphorylation states
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