TAP General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity. Belongs to the VDP/USO1/EDE1 family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis; Vesicle
Cellular Component:  cytosol; extrinsic component of Golgi membrane; fibrillar center; perinuclear region of cytoplasm
Molecular Function:  identical protein binding
Biological Process:  Golgi organization; inter-Golgi cisterna vesicle-mediated transport; intracellular protein transport; protein homooligomerization; regulation of cellular response to insulin stimulus; secretory granule localization; small GTPase mediated signal transduction; vesicle fusion with Golgi apparatus
Reference #:  P41541 (UniProtKB)
Alt. Names/Synonyms: General vesicular transport factor p115; TAP; Transcytosis associated protein; USO1; USO1 vesicle transport factor; VDP; Vesicle docking protein
Gene Symbols: USO1
Molecular weight: 107,515 Da
Basal Isoelectric point: 4.84  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein