K7 a type II cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Phosphorylation of keratins at specific sites affects their organization, assembly dynamics, and their interaction with signaling molecules. Specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 12q13.13
Cellular Component:  cytoplasm; cytosol; intermediate filament; keratin filament
Molecular Function:  protein binding; structural molecule activity
Biological Process:  cornification; keratinization; viral process
Reference #:  P08729 (UniProtKB)
Alt. Names/Synonyms: CK-7; CK7; cytokeratin 7; Cytokeratin-7; K2C7; K7; keratin 7; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7; Keratin, type II cytoskeletal 7; Keratin-7; KRT7; MGC129731; MGC3625; Sarcolectin; SCL; type II mesothelial keratin K7; Type-II keratin Kb7
Gene Symbols: KRT7
Molecular weight: 51,386 Da
Basal Isoelectric point: 5.4  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein