abLIM iso2
May act as scaffold protein. May play a role in the development of the retina. Has been suggested to play a role in axon guidance. Detected in liver, heart, skeletal muscle, brain and retina, where it is concentrated in the inner segment and in the outer plexiform layers. 6 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Actin-binding; Cytoskeletal; Motility/polarity/chemotaxis |
Chromosomal Location of human Ortholog: 10q25.3 |
Cellular Component:
actin cytoskeleton; cytoplasm; lamellipodium; stress fiber
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Molecular Function:
actin binding; actin filament binding; metal ion binding; protein binding
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Biological Process:
animal organ morphogenesis; cilium assembly; cytoskeleton organization; lamellipodium assembly; visual perception
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Reference #:
O14639-2
(UniProtKB)
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Alt. Names/Synonyms: ABLIM; abLIM iso2; abLIM-1; ABLIM1; ABLM1; actin binding LIM protein 1; Actin-binding double zinc finger protein; actin-binding double-zinc-finger protein; Actin-binding LIM protein 1; Actin-binding LIM protein family member 1; KIAA0059; LIMAB1; Limatin
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Gene Symbols: ABLIM1
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Molecular weight:
81,121 Da
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Basal Isoelectric point:
8.44
Predict pI for various phosphorylation states
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