NEU3 Plays a role in modulating the ganglioside content of the lipid bilayer at the level of membrane-bound sialyl glycoconjugates. Belongs to the glycosyl hydrolase 33 family. Note: This description may include information from UniProtKB.
Protein type: EC; Glycan Metabolism - other glycan degradation; Hydrolase; Lipid Metabolism - sphingolipid
Chromosomal Location of Human Ortholog: 11q13.4
Cellular Component:  cytoplasm; intracellular membrane-bound organelle; membrane; plasma membrane
Molecular Function:  alpha-sialidase activity; exo-alpha-sialidase activity
Biological Process:  carbohydrate metabolic process; ganglioside catabolic process; glycosphingolipid metabolic process; oligosaccharide catabolic process
Reference #:  Q9UQ49 (UniProtKB)
Alt. Names/Synonyms: FLJ12388; Ganglioside sialidase; Membrane sialidase; N-acetyl-alpha-neuraminidase 3; NEU3; NEUR3; neuraminidase 3; SIAL3; sialidase 3 (membrane sialidase); Sialidase-3
Gene Symbols: NEU3
Molecular weight: 48,252 Da
Basal Isoelectric point: 6.78  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene