BDP1 Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues. Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily. Expressed in brain, colon and several tumor-derived cell lines. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC 3.1.3.48; Motility/polarity/chemotaxis; Protein phosphatase, tyrosine (non-receptor)
Chromosomal Location of Human Ortholog: 9q21
Cellular Component:  cytoplasm; nucleus
Molecular Function:  non-membrane spanning protein tyrosine phosphatase activity; protein tyrosine phosphatase activity
Biological Process:  blastocyst formation; peptidyl-tyrosine dephosphorylation
Reference #:  P70602 (UniProtKB)
Alt. Names/Synonyms: BDP1; MGC112761; MGC112828; Protein tyrosine phosphatase 20; protein tyrosine phosphatase, non-receptor type 18; PTP20; Ptpn18
Gene Symbols: Ptpn18
Molecular weight: 50,107 Da
Basal Isoelectric point: 8.74  Predict pI for various phosphorylation states
CST Pathways:  ErbB/HER Signaling
Select Structure to View Below

BDP1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene