NRK May phosphorylate cofilin-1 and induce actin polymerization through this process, during the late stages of embryogenesis. Involved in the TNF-alpha-induced signaling pathway. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC; Kinase, protein; MSN subfamily; Protein kinase, STE; Protein kinase, Ser/Thr (non-receptor); STE group; STE20 family
Chromosomal Location of human Ortholog: Xq22.3
Cellular Component: 
Molecular Function:  ATP binding
Biological Process:  activation of JNKK activity; negative regulation of cell proliferation; parturition; regulation of spongiotrophoblast cell proliferation
Reference #:  Q7Z2Y5 (UniProtKB)
Alt. Names/Synonyms: DKFZp686A17109; FLJ16788; MGC131849; NESK; Nik related kinase; Nik-related protein kinase; NRK; ZC4
Gene Symbols: NRK
Molecular weight: 178,479 Da
Basal Isoelectric point: 5.93  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  CCLE  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  KinBase  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene