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TKT iso2
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. Belongs to the transketolase family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Carbohydrate Metabolism - pentose phosphate pathway; EC 2.2.1.1; Transferase |
| Chromosomal Location of human Ortholog: 3p21.1 |
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Cellular Component:
cytosol; endoplasmic reticulum membrane; nuclear body; nucleoplasm; peroxisome
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Molecular Function:
calcium ion binding; magnesium ion binding; protein binding; protein homodimerization activity; thiamine pyrophosphate binding; transketolase activity
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Biological Process:
glyceraldehyde-3-phosphate biosynthetic process; pentose-phosphate shunt; pentose-phosphate shunt, non-oxidative branch; regulation of growth; xylulose 5-phosphate biosynthetic process
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Reference #:
P29401-2
(UniProtKB)
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Alt. Names/Synonyms: epididymis luminal protein 107; epididymis secretory protein Li 48; HEL-S-48; HEL107; SDDHD; TK; TKT; TKT iso2; TKT1; Transketolase
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Gene Symbols: TKT
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Molecular weight:
68,814 Da
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Basal Isoelectric point:
7.25
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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