STX1B Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. Belongs to the syntaxin family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Vesicle
Chromosomal Location of Human Ortholog: 7|7 F3
Cellular Component:  axon; centrosome; cytoplasm; endomembrane system; integral component of membrane; membrane; neuromuscular junction; nuclear lamina; nucleoplasm; nucleus; plasma membrane; presynapse; presynaptic active zone membrane; presynaptic membrane; SNARE complex; synaptic vesicle
Molecular Function:  protein binding; protein domain specific binding; protein kinase binding; signaling receptor binding; SNAP receptor activity; SNARE binding
Biological Process:  calcium ion-regulated exocytosis of neurotransmitter; exocytic insertion of neurotransmitter receptor to postsynaptic membrane; exocytosis; intracellular protein transport; negative regulation of synaptic vesicle recycling; neurotransmitter transport; positive regulation of excitatory postsynaptic potential; positive regulation of neurotransmitter secretion; positive regulation of spontaneous neurotransmitter secretion; protein localization to membrane; protein transport; regulation of exocytosis; regulation of gene expression; regulation of synaptic vesicle priming; spontaneous neurotransmitter secretion; synaptic vesicle docking; synaptic vesicle exocytosis; synaptic vesicle fusion to presynaptic active zone membrane; vesicle docking; vesicle docking involved in exocytosis; vesicle fusion; vesicle-mediated transport
Reference #:  P61264 (UniProtKB)
Alt. Names/Synonyms: Stx1b; Stx1b1; Stx1b2; Stx1bl; Syn1b; syntaxin 1B; syntaxin 1B1; syntaxin 1B2; Syntaxin-1B
Gene Symbols: Stx1b
Molecular weight: 33,245 Da
Basal Isoelectric point: 5.25  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein