STC2 Has an anti-hypocalcemic action on calcium and phosphate homeostasis. Belongs to the stanniocalcin family. Expressed in a variety of tissues including muscle, heart, pancreas, kidney, spleen, prostate, small intestine, colon and peripheral blood leukocytes. Note: This description may include information from UniProtKB.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of mouse Ortholog: 11|11 A4
Cellular Component:  endoplasmic reticulum; extracellular region; Golgi apparatus; perinuclear region of cytoplasm
Molecular Function:  enzyme binding; heme binding; hormone activity; protein binding; protein homodimerization activity
Biological Process:  calcium ion homeostasis; cellular calcium ion homeostasis; endoplasmic reticulum unfolded protein response; negative regulation of gene expression; negative regulation of multicellular organism growth; regulation of hormone biosynthetic process; regulation of sodium-dependent phosphate transport; regulation of store-operated calcium entry; response to endoplasmic reticulum stress; response to oxidative stress
Reference #:  O88452 (UniProtKB)
Alt. Names/Synonyms: AW125853; mustc; mustc2; OTTMUSP00000005531; stanniocalcin 2; stanniocalcin 2-like; Stanniocalcin-2; Stc; STC-2; Stc2; Stc2l
Gene Symbols: Stc2
Molecular weight: 32,602 Da
Basal Isoelectric point: 6.42  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene