G-gamma 12
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Belongs to the G protein gamma family. Note: This description may include information from UniProtKB.
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Protein type: G protein; G protein, heterotrimeric; G protein, heterotrimeric gamma |
Cellular Component:
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Molecular Function:
PDZ domain binding
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Reference #:
Q28024
(UniProtKB)
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Alt. Names/Synonyms: G-gamma 12; Gamma-S1; GBG12; GBGC; GNG12; GNGT12; Guanine nucleotide-binding protein G; Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-12 subunit; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
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Gene Symbols: GNG12
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Molecular weight:
8,057 Da
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Basal Isoelectric point:
9.14
Predict pI for various phosphorylation states
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CST Pathways:
GPCR Signaling to MAPKs
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Parkinson's Disease
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Phospholipase Signaling
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PI3K/Akt Signaling
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SAPK/JNK Signaling Cascades
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